Construction and Validation of an Early Warning Model for Predicting the 28-Day Mortality in Sepsis Patients with Chronic Obstructive Pulmonary Disease

This nomogram integrates laboratory indicators pertinent to the patient's metabolic status, hypoxia status, and organ function, thereby enhancing the accuracy of early prediction of 28-day mortality in sepsis patients with COPD. Additionally, the model's comparative advantage over existing scoring systems (eg, SOFA) would enhance its impact. Our findings hold substantial implications for early prognostic assessment and clinical decision-making in this patient population. Therefore, earlier diagnosis within 24 hours of admission and proper identification of high-risk patients may reduce disease-related mortality by promoting timely treatment.