The kynurenine pathway and markers of neurodegeneration and cerebral small vessel disease: The Maastricht Study
These findings suggest that several kynurenines are associated with neurodegeneration in community-dwelling older adults, but not with cerebrovascular damage.
Authors
- Anke Wesselius (ORCID: https://orcid.org/0000-0003-4474-9665)
- Arve Ulvik (ORCID: https://orcid.org/0000-0003-1574-9690)
- Jacobus F.A. Jansen (ORCID: https://orcid.org/0000-0002-5271-8060)
- Marleen M. J. van Greevenbroek (ORCID: https://orcid.org/0000-0002-2989-1631)
- Per Magne Ueland (ORCID: https://orcid.org/0000-0002-1903-0571)
- Casper G. Schalkwijk (ORCID: https://orcid.org/0000-0003-0190-2690)
- Miranda T. Schram (ORCID: https://orcid.org/0000-0001-8113-7604)
- Walter H. Backes (ORCID: https://orcid.org/0000-0001-7905-0681)
- Frans R.J. Verhey (ORCID: https://orcid.org/0000-0002-8307-8406)
- Inez H.G.B. Ramakers (ORCID: https://orcid.org/0000-0002-4747-2879)
- Lieke Bakker (ORCID: https://orcid.org/0000-0002-2160-7018)
- Carla Kallen (ORCID: https://orcid.org/0000-0003-1468-8793)
- Simone J. P. M. Eussen (ORCID: https://orcid.org/0000-0003-0559-6838)
- Sebastian Köhler (ORCID: https://orcid.org/0000-0002-2398-0609)
Institutions
- Maastricht University Medical Centre (NL)
- Maastricht University (NL)
- Bevital (Norway) (NO)
Publication Details
- Journal
- Journal of the Neurological Sciences
- Published
- 2025-05-06
- DOI
- https://doi.org/10.1016/j.jns.2025.123522
- Citations
- 1
- Primary Topic
- Tryptophan and brain disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.58
Funders
- Sanofi
- Health Foundation Limburg
- Novo Nordisk
- European Regional Development Fund
- CARIM School for Cardiovascular Diseases, Universiteit Maastricht
- Care and Public Health Research Institute, Universiteit Maastricht
- NUTRIM School of Nutrition and Translational Research in Metabolism
- Cilag