Venlafaxine-PLGA nanoparticles provide a fast onset of action in an animal model of depression via nose-to-brain
These findings indicated that intranasal venlafaxine-loaded poly(lactic-coglycolic acid) nanoparticles could become a viable technique for improving venlafaxine brain uptake via nose-to-brain. It could also be a promising nanoplatform for enhancing the treatment of depression.
Authors
- Irene Suárez‐Pereira (ORCID: https://orcid.org/0000-0003-3559-5852)
- José Manuel Pérez Montesinos
- Lucía Martín‐Banderas (ORCID: https://orcid.org/0000-0003-1447-6125)
- María Dolores Cayero Otero (ORCID: https://orcid.org/0000-0001-7024-2783)
- Alejandra Delgado-Sequera (ORCID: https://orcid.org/0000-0003-0675-413X)
- María Hidalgo‐Figueroa (ORCID: https://orcid.org/0000-0001-5241-0931)
- Laura Pérez-Caballero (ORCID: https://orcid.org/0000-0002-2315-2213)
- Esther Berrocoso (ORCID: https://orcid.org/0000-0003-0208-7472)
Institutions
- Universidad de Granada (ES)
- Centro de Investigación Biomédica en Red de Salud Mental (ES)
- Biomedical Research and Innovation Institute of Cadiz (ES)
- Instituto de Biomedicina de Sevilla (ES)
- Hospital Universitario Puerto Real (ES)
- Hospital Universitario Virgen del Rocío (ES)
- Universidad de Sevilla (ES)
Publication Details
- Journal
- International Journal of Pharmaceutics
- Published
- 2025-05-06
- DOI
- https://doi.org/10.1016/j.ijpharm.2025.125692
- Citations
- 5
- Primary Topic
- Supramolecular Self-Assembly in Materials
- Type
- article
- Field-Weighted Citation Impact
- 2.99
Funders
- Universidad de Sevilla
- Consejería de Economía, Conocimiento, Empresas y Universidad, Junta de Andalucía
- Junta de Andalucía