Cabergoline-induced cerebrospinal fluid fistulae in macroprolactinomas

The optimal management of CSF fistulae due to tumor shrinkage of macroprolactinomas after dopamine agonist therapy remains to be defined. Exceptionally, medication-induced CSF fistulae in response to tumor shrinkage may close spontaneously without recurrence. If persistent, transnasal-transsphenoidal closure of CSF fistulae represents an efficient treatment and dopamine agonist treatment may be continued. Thus, we recommend early surgical repair.

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Publication Details

Journal
Langenbeck s Archives of Surgery
Published
2025-05-06
DOI
https://doi.org/10.1007/s00423-025-03722-8
Citations
2
Primary Topic
Pituitary Gland Disorders and Treatments
Type
article
Field-Weighted Citation Impact
2.59
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article

Cabergoline-induced cerebrospinal fluid fistulae in macroprolactinomas

Thomas M. Kinfe, Makoto Nakamura, Holger Leitolf, Stefan Stolle et al.
2 citations
Langenbeck s Archives of Surgery
Pituitary Gland Disorders and Treatments
2.59
article

Cabergoline-induced cerebrospinal fluid fistulae in macroprolactinomas

Thomas M. Kinfe, Makoto Nakamura, Holger Leitolf, Stefan Stolle, Rudolf Fahlbusch, Christoph Terkamp, S. Hertz, Elvis J. Hermann, J Krauß
article en
2 citations

Abstract

The optimal management of CSF fistulae due to tumor shrinkage of macroprolactinomas after dopamine agonist therapy remains to be defined. Exceptionally, medication-induced CSF fistulae in response to tumor shrinkage may close spontaneously without recurrence. If persistent, transnasal-transsphenoidal closure of CSF fistulae represents an efficient treatment and dopamine agonist treatment may be continued. Thus, we recommend early surgical repair.

Langenbeck s Archives of SurgeryVol. 410(1)
Heidelberg University (DE), University Hospital Heidelberg (DE), Medizinische Hochschule Hannover (DE), International Neuroscience Institute (DE), Lungenklinik Köln-Merheim (DE), University Medical Centre Mannheim (DE)
Good health and well-being
Openalex Percentile: Top 10%
Pituitary Gland Disorders and Treatments
2.59
DOIOpen Access PDFOpenAlex
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Cabergoline-induced cerebrospinal fluid fistulae in macroprolactinomas — Thomas M. Kinfe, Makoto Nakamura, et al. · Langenbeck s Archives of Surgery (2025) | TGRS Research Map | TGRS