Longitudinal Associations Between Baseline Sarcopenia and Knee Osteoarthritis Progression and Risk of Knee Replacement
Scre-S and Prob-S were significantly and longitudinally associated with both radiographic and symptomatic progression in KOA and subsequent KR. Our findings indicated a potential causal role of sarcopenia in KOA progression and highlighted its potentially therapeutic effect in KOA management.
Authors
- Weijie Zhou (ORCID: https://orcid.org/0000-0002-0021-9454)
- Jianxiao Xie (ORCID: https://orcid.org/0009-0005-5700-8868)
- Changhai Ding (ORCID: https://orcid.org/0000-0002-9479-730X)
- Guangming Tao (ORCID: https://orcid.org/0000-0002-1371-7735)
- Peihua Cao (ORCID: https://orcid.org/0000-0003-4269-3899)
- Tianxing Wu
- Qin Dang (ORCID: https://orcid.org/0000-0002-2521-625X)
- Zhixiang Cai (ORCID: https://orcid.org/0000-0003-2192-1186)
- Taiwei Wang (ORCID: https://orcid.org/0009-0009-6453-2042)
- Zhaohua Zhu (ORCID: https://orcid.org/0000-0003-3913-2564)
- David John Hunter (ORCID: https://orcid.org/0000-0003-3197-752X)
- Rocco Barazzoni (ORCID: https://orcid.org/0000-0002-4049-2404)
- Jian Wang (ORCID: https://orcid.org/0000-0003-3967-470X)
- Jia Li (ORCID: https://orcid.org/0000-0003-3572-3690)
- Weiyu Han (ORCID: https://orcid.org/0000-0003-1590-7433)
- Xiaoshuai Wang (ORCID: https://orcid.org/0000-0002-3895-1384)
- Jie Chen (ORCID: https://orcid.org/0000-0003-0266-0929)
Institutions
- The University of Sydney (AU)
- University of Tasmania (AU)
- University of Trieste (IT)
- Royal North Shore Hospital (AU)
- Nanfang Hospital (CN)
- Zhujiang Hospital (CN)
- Dongguan People’s Hospital (CN)
- Community Health Center (US)
- Southern Medical University (CN)
Publication Details
- Journal
- Arthritis & Rheumatology
- Published
- 2025-05-06
- DOI
- https://doi.org/10.1002/art.43213
- Citations
- 4
- Primary Topic
- Nutrition and Health in Aging
- Type
- article
- Field-Weighted Citation Impact
- 4.66