A Multicenter, Randomized, Controlled, Clinical Trial Evaluating a Lyopreserved Amniotic Membrane in the Treatment of Venous Leg Ulcers
LPM and standard of care, significantly closed more venous leg ulcers and faster than standard of care alone and improved the quality of life for patients, suggesting that the use of aseptically processed LPM is a safe and effective treatment option in the healing of chronic venous leg ulcers. <b>Trial Registration:</b> ClinicalTrials.gov ID: NCT03629236, Study to Evaluate Safety and Efficacy of GrafixPL for the Treatment of Venous Leg Ulcers. (https://clinicaltrials.gov/study/NCT03629236).
Authors
- Felix Sigal
- Molly Saunders (ORCID: https://orcid.org/0000-0003-0330-7430)
- Mher Vartivarian (ORCID: https://orcid.org/0000-0002-7160-8289)
- Jaideep Banerjee (ORCID: https://orcid.org/0000-0002-8688-7137)
- Gregory Tovmassian (ORCID: https://orcid.org/0000-0002-5368-1095)
- Lesly Robinson
- A Jack Grossman
- Alexander M. Reyzelman (ORCID: https://orcid.org/0000-0003-2642-6184)
- Francisco Perez‐Clavijo
- Lena Levine
- Shawn Cazzell
- Yadwinder Dhillon
- Robert S. Kirsner
- Francis Wodie
Institutions
- University of Miami (US)
- Heritage Preservation (US)
- Med Center (US)
- Clinical Solutions (US)
- Center for Clinical Research (United States) (US)
- Temple University (US)
- Osiris Therapeutics (United States) (US)
Publication Details
- Journal
- Health Science Reports
- Published
- 2025-05-01
- DOI
- https://doi.org/10.1002/hsr2.70819
- Citations
- 1
- Primary Topic
- Diagnosis and Treatment of Venous Diseases
- Type
- article
- Field-Weighted Citation Impact
- 2.01
Funders
- Osiris Therapeutics