Novel Application of T1ρ Magnetic Resonance Imaging for Noninvasive Assessment of Bladder Hyperpermeability Biomarkers: A Focus on Glycosaminoglycan Content
T1ρ MRI accurately measured glycosaminoglycans in rat bladders and differentiated protamine sulfate-treated bladder biopsies from unperturbed specimens in humans. T1ρ MRI warrants further investigation as a novel biomarker of bladder glycosaminoglycan content in interstitial cystitis/bladder pain syndrome.
Authors
- Christine B. Chung (ORCID: https://orcid.org/0000-0002-0821-5458)
- Yajun Ma (ORCID: https://orcid.org/0000-0003-0830-9232)
- Jennifer T. Anger
- Sheronda Statum
- Aurea V. R. Mohana‐Borges (ORCID: https://orcid.org/0000-0001-8853-0820)
- Jeffrey D. Esko (ORCID: https://orcid.org/0000-0001-8322-1834)
- Xin Cheng
- Marianna Alperin (ORCID: https://orcid.org/0000-0002-6004-1803)
- Julie A. Suyama (ORCID: https://orcid.org/0009-0009-9017-2490)
Institutions
- University of California San Diego (US)
- Sanford Consortium for Regenerative Medicine (US)
Publication Details
- Journal
- Neurourology and Urodynamics
- Published
- 2025-05-04
- DOI
- https://doi.org/10.1002/nau.70058
- Primary Topic
- Urinary Bladder and Prostate Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00