Phosphaturic mesenchymal tumor of the skull base presenting with tumor-induced osteomalacia and multiple fractures: a case report

Phosphaturic mesenchymal tumors include rare cranial base neoplasms that are often overlooked due to their nonspecific symptoms. Accurate diagnosis requires a comprehensive assessment, encompassing systemic evaluation, laboratory tests, imaging studies, and microscopic examination. This case demonstrates the innovative use of anlotinib capsules in the treatment of PMTs. After 2 years, no recurrence was observed, and the patient returned to normal life. Effective management of this condition necessitates a multidisciplinary approach involving otolaryngologists, radiologists, nuclear medicine specialists, and pathologists.

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Publication Details

Journal
Journal of Medical Case Reports
Published
2025-05-05
DOI
https://doi.org/10.1186/s13256-025-05244-9
Primary Topic
Parathyroid Disorders and Treatments
Type
article
Field-Weighted Citation Impact
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article

Phosphaturic mesenchymal tumor of the skull base presenting with tumor-induced osteomalacia and multiple fractures: a case report

Zhiqing He, Qianhui Qiu, Minghui Zhang, Wang Keshuang et al.
Journal of Medical Case Reports
Parathyroid Disorders and Treatments
article

Phosphaturic mesenchymal tumor of the skull base presenting with tumor-induced osteomalacia and multiple fractures: a case report

Zhiqing He, Qianhui Qiu, Minghui Zhang, Wang Keshuang, Qin Jiace
article en

Abstract

Phosphaturic mesenchymal tumors include rare cranial base neoplasms that are often overlooked due to their nonspecific symptoms. Accurate diagnosis requires a comprehensive assessment, encompassing systemic evaluation, laboratory tests, imaging studies, and microscopic examination. This case demonstrates the innovative use of anlotinib capsules in the treatment of PMTs. After 2 years, no recurrence was observed, and the patient returned to normal life. Effective management of this condition necessitates a multidisciplinary approach involving otolaryngologists, radiologists, nuclear medicine specialists, and pathologists.

Journal of Medical Case ReportsVol. 19(1)
Guangdong Academy of Medical Sciences (CN), Guangdong Provincial People's Hospital (CN), Southern Medical University (CN)
Openalex Percentile: Top 89%
Parathyroid Disorders and Treatments
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