The Soluble Platelet‐Derived Growth Factor β Receptor Induces Postoperative Delirium by Downregulating the Clearance of β‐Amyloid in the Brain

The results suggest that the increase in CSF sPDGFRβ is associated with an increased risk of POD due to the blood-brain barrier (BBB) dysfunction and reduced Aβ42 clearance. In this study, the correlation between CSF sPDGFRβ and POD was investigated for the first time, providing a new reference index for POD prediction. However, this paper did not study other relevant indicators of the BBB and lacked follow-up, which could be further improved in the future.