Prognostic Significance of Elevated Platelet Count (>200 x 10^9 per L) in BCLC Stages B and C of Hepatocellular Carcinoma: A Retrospective Multicenter Analysis
Platelet counts showed a stage-dependent prognostic impact in HCC. A platelet count above a cutoff of 200/µL at diagnosis was associated with poorer prognosis. Using this cutoff may improve survival prediction in BCLC B and C patients with potential usage for risk stratification and guidance of treatment decisions. Further external validation is required to confirm these findings and evaluate their clinical applicability.
Authors
- Florian Paul Reiter (ORCID: https://orcid.org/0000-0003-3807-1456)
- Alexander B. Philipp (ORCID: https://orcid.org/0000-0002-0215-9977)
- Julia V. Mayerle (ORCID: https://orcid.org/0000-0002-3666-6459)
- Najib Ben Khaled (ORCID: https://orcid.org/0000-0002-9681-2542)
- Christel Weiß (ORCID: https://orcid.org/0000-0002-8692-5690)
- Katharina Pomej (ORCID: https://orcid.org/0000-0002-2807-3565)
- Kathrin Bernhart
- Enrico Narciso De Toni (ORCID: https://orcid.org/0000-0002-8101-8207)
- Stefan Munker (ORCID: https://orcid.org/0000-0002-1305-162X)
- Isaac Rodriguez (ORCID: https://orcid.org/0000-0002-2529-7408)
- Daniel Nasseh (ORCID: https://orcid.org/0000-0002-2167-3146)
- Murat Fındık (ORCID: https://orcid.org/0000-0003-1408-2548)
- Lisa Katrin Siegmund
- Daniel Roessler (ORCID: https://orcid.org/0000-0002-5652-5987)
- Max Seidensticker (ORCID: https://orcid.org/0000-0002-2481-5410)
- Lorenz Balcar (ORCID: https://orcid.org/0000-0002-6708-3061)
- Liangtao Ye (ORCID: https://orcid.org/0000-0003-4364-9494)
- B Scheiner
Institutions
- Heidelberg University (DE)
- University Hospital Heidelberg (DE)
- LMU Klinikum (DE)
- Universitätsklinikum Würzburg (DE)
- University Medical Centre Mannheim (DE)
- Medical University of Vienna (AT)
- Ludwig-Maximilians-Universität München (DE)
Publication Details
- Journal
- Journal of Hepatocellular Carcinoma
- Published
- 2025-05-01
- DOI
- https://doi.org/10.2147/jhc.s511263
- Citations
- 1
- Primary Topic
- Inflammatory Biomarkers in Disease Prognosis
- Type
- article
- Field-Weighted Citation Impact
- 1.05