The Potential Mechanisms of Althaea rosea (Linn.) Cavan. Flower in Alleviating Tetrodotoxin Poisoning: An Integrated Metabolomics, Network Pharmacology and Experimental Validation
EAEAR alleviates TTX poisoning symptoms by modulating targets and metabolites in the arginine and proline metabolism pathways and the arginine biosynthesis pathway. This study provides a theoretical basis for further exploration of its therapeutic potential and mechanisms against TTX poisoning.
Authors
- Youjia Wu (ORCID: https://orcid.org/0000-0002-8511-6250)
- Renjin Zheng (ORCID: https://orcid.org/0000-0001-7242-9621)
- Fanxiang Zeng
- Lingyi Huang (ORCID: https://orcid.org/0000-0002-1794-5698)
- Liying Huang
Institutions
- Fujian Medical University (CN)
Publication Details
- Journal
- Drug Design Development and Therapy
- Published
- 2025-05-01
- DOI
- https://doi.org/10.2147/dddt.s505270
- Primary Topic
- Alkaloids: synthesis and pharmacology
- Type
- article
- Field-Weighted Citation Impact
- 0.00