Boswellia carteri Birdw. Resin Extract Induces Phase-I Cytochrome P-450 Enzyme Gene Expressions in Human Hepatocarcinoma (Hep G2) Cells: In vitro and in silico Studies
In conclusion, there is a potential for interactions between <i>B. carteri</i> resins and pharmaceuticals metabolized by CYP enzymes; thus, we advise caution to consumers, patients, and healthcare providers regarding their concomitant use. Although our findings provide valuable insights, further in vivo studies are essential to validate the modulatory effects of <i>B. carteri</i> on CYP gene expression.
Authors
- Rasha Saad Suliman (ORCID: https://orcid.org/0000-0002-6323-0781)
- Amani R. Alsharidah (ORCID: https://orcid.org/0000-0002-3199-0428)
- Sahar S. Alghamdi (ORCID: https://orcid.org/0000-0002-2770-218X)
- Zeyad Alehaideb (ORCID: https://orcid.org/0000-0002-7185-2820)
- Hussah N Albahlal
- Raghad Saleh Alajmi
- Aljawharah Almogren (ORCID: https://orcid.org/0000-0003-1372-9645)
Institutions
- King Saud bin Abdulaziz University for Health Sciences (SA)
- King Saud University (SA)
- King Abdullah International Medical Research Center (SA)
- National Guard Health Affairs (SA)
Publication Details
- Journal
- Biologics
- Published
- 2025-05-01
- DOI
- https://doi.org/10.2147/btt.s491278
- Citations
- 1
- Primary Topic
- Pharmacological Effects of Medicinal Plants
- Type
- article
- Field-Weighted Citation Impact
- 1.39