Prevalence of Bisphosphonate and Denosumab Use in Elderly Care Facilities: Implications for the Management of Medication-Related Osteonecrosis of the Jaw
In these elderly facilities, 9.8% of residents used BPs or Dmab, with 15.6% receiving injectable formulations. One MRONJ case occurred with injectable BP use, suggesting the potential for sporadic MRONJ in elderly care. As BP/Dmab use is likely to increase, pharmacist intervention for prescription review and training for visiting dentists are considered effective strategies for MRONJ prevention and early detection.
Authors
- Takahiro Kaneko (ORCID: https://orcid.org/0000-0001-6046-8228)
- Miki Yamada (ORCID: https://orcid.org/0000-0002-7980-5156)
- Masako Kanbe
- Shunsuke Hino (ORCID: https://orcid.org/0000-0002-9690-1713)
- Norio Horie (ORCID: https://orcid.org/0009-0001-1354-9313)
- Yosuke Iijima (ORCID: https://orcid.org/0000-0002-3804-6122)
- Kiyoko Ariya
- Tomoyuki Kanbe (ORCID: https://orcid.org/0009-0002-5121-1919)
- Motohiko Sano
Institutions
- Jichi Medical University (JP)
- Hoshi University (JP)
- Saitama Municipal Hospital (JP)
- Jichi Medical University Saitama Medical Center (JP)
- Saitama Medical University (JP)
Publication Details
- Journal
- Cureus
- Published
- 2025-05-05
- DOI
- https://doi.org/10.7759/cureus.83490
- Citations
- 1
- Primary Topic
- Bone health and treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.05