SYSTEMS MEDICINE: DIAGNOSTIC MODEL OF PSYCHOPATHOLOGY AND CLINICAL MEDICINE

Introduction: Systems medicine is an approach to understanding disease through the integration of large patient data sets, integrating data with clinical measurements, which have the potential to impact our understanding of the molecular basis and management of a disease. Objective: To present a new model of Systems Medicine, which is based on neuroscience and human neurobiology, which presents the robustness of empiricism, and which addresses groups of diagnoses of chronic comorbidities, which are linked to neuropsychological symptoms, such as stress, psychosocial factors and family conflicts in an objective manner. Methods: The clinical neuroscience of family interactions and childhood adversities develops a three-level neuromaladaptive connectome through common biobehaviors, which represents a structure delimited in personality traits, which were identified in empirical observation and constructed a new model. Results: A clinical synthesis associated with organic pathophysiology, we organized a diagnostic systems medicine model, with grouping of individuals that addresses objective neuropsychological alterations associated with changes in chronic comorbidities of clinical medicine. Discussion: This method organizes the clinical approach to the family factor, which is neurodysfunctional and represents a promising tool, but is in its infancy of theoretical basis, which requires experimental evaluation. Conclusion: The model is a new instrument for new scientific research and assists in the scientific advancement of family medicine, mental health policies, and the creation of mental health care plans in primary care, which is currently lacking.