Clinical, Electroencephalogram and Imaging Characteristics of Patients With Anti‐LGI1 Antibody Encephalitis: A Multicenter Cohort Study

Baseline mRS scores and low-frequency power in the frontotemporal region showed a positive correlation with anti-LGI1 antibody titers, suggesting that antibody levels may reflect disease severity in LGI1 autoimmune encephalitis. Further studies are warranted to validate these associations in prospective multicenter cohorts.

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Publication Details

Journal
CNS Neuroscience & Therapeutics
Published
2025-05-01
DOI
https://doi.org/10.1111/cns.70414
Citations
3
Primary Topic
Autoimmune Neurological Disorders and Treatments
Type
article
Field-Weighted Citation Impact
4.17

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article

Clinical, Electroencephalogram and Imaging Characteristics of Patients With Anti‐LGI1 Antibody Encephalitis: A Multicenter Cohort Study

Meng Zhao, Shufen Chen, Yue Yuan, Ke‐Liang Chen et al.
3 citations
CNS Neuroscience & Therapeutics
Autoimmune Neurological Disorders and Treatments
4.17
article

Clinical, Electroencephalogram and Imaging Characteristics of Patients With Anti‐LGI1 Antibody Encephalitis: A Multicenter Cohort Study

Meng Zhao, Shufen Chen, Yue Yuan, Ke‐Liang Chen, Mei Cui, Li Sun, Rongze Wang, Haining Zhang, Mengmeng Li, Yan Zhang, Hui Tian, Zhao Yang, Jin‐Tai Yu, Yuyuan Huang
article en
3 citations

Abstract

Baseline mRS scores and low-frequency power in the frontotemporal region showed a positive correlation with anti-LGI1 antibody titers, suggesting that antibody levels may reflect disease severity in LGI1 autoimmune encephalitis. Further studies are warranted to validate these associations in prospective multicenter cohorts.

CNS Neuroscience & TherapeuticsVol. 31(5)
Jilin University (CN), Fudan University (CN), First Hospital of Jilin University (CN), Huashan Hospital (CN), State Key Laboratory of Medical Neurobiology
Natural Science Foundation of Jilin Province, National Natural Science Foundation of China, Huashan Hospital, Program of Shanghai Academic Research Leader
Good health and well-being
Openalex Percentile: Top 6%
Autoimmune Neurological Disorders and Treatments
4.17
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Clinical, Electroencephalogram and Imaging Characteristics of Patients With Anti‐LGI1 Antibody Encephalitis: A Multicenter Cohort Study — Meng Zhao, Shufen Chen, et al. · CNS Neuroscience & Therapeutics (2025) | TGRS Research Map | TGRS