Methamphetamine‐Associated Pulmonary Arterial Hypertension Is Associated With Worse Right Ventricular Function Than Idiopathic Pulmonary Arterial Hypertension: A Matched Study
Despite a similar mPAP, patients with MA-PAH had more RA dilation, RV dilation, lower RV systolic/diastolic function, and worse RA and RV mechanics as assessed by strain compared to patients with I-PAH. Our findings suggest that, in addition to causing remodeling of the pulmonary vasculature, methamphetamine may have a direct cardiotoxic effect on the right heart.
Authors
- Nathan Hatton
- Benjamin Kogelschatz
- Emily Beck (ORCID: https://orcid.org/0000-0003-3186-1463)
- Katharine Clapham (ORCID: https://orcid.org/0000-0003-3659-4755)
- Elizabeth Dranow (ORCID: https://orcid.org/0000-0002-5324-192X)
- Dana Klanderud
- Jennalyn D. Mayeux
- Dai‐Yin Lu (ORCID: https://orcid.org/0000-0002-2619-1242)
- Dominique Ingram
- Christy Ma
- Satvik Ramakrishna (ORCID: https://orcid.org/0000-0002-5143-6010)
- John J. Ryan
- Eileen O’Neill
Institutions
- University of Utah (US)
Publication Details
- Journal
- Echocardiography
- Published
- 2025-05-01
- DOI
- https://doi.org/10.1111/echo.70180
- Citations
- 4
- Primary Topic
- Pulmonary Hypertension Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 6.07