NEUROCARDIOLOGY: PATHOPHYSIOLOGICAL MECHANISMS IN MYOCARDIAL INFARCTION IN YOUNG PATIENTS AND IN ACUTE CARDIOVASCULAR EVENTS WITH EMOTIONAL INFLUENCE

Introduction: Notably, a phenomenon of increased early incidence of some diseases is without control and real understanding, affecting young adults and adolescents, as in the case of obesity, colon cancer, metabolic syndrome, and acute myocardial infarction (AMI). Although the mortality rate of AMI has decreased, it is currently increasingly common to find young people diagnosed with AMI; studies have already shown this increase in incidence in this age group. Objective: The integration of intricate processes of genetic pathways related to lipid metabolism, inflammation, and coagulation helps in the understanding and identification of early AMI (IAMP), in addition to guiding primary prevention strategies. Methodology: A clinical synthesis with theoretical implications was performed, based on neurobiological and neurogenomic mechanisms, which presents the integration of maladaptive neuroscience with cardiology. Results: By reviewing the data on the risk factors of IAMP, its little-known pathophysiological processes, we identified its possible relationship with psychosocial stress, which can currently be assessed through a clinic focused on clinical neuromarkers related to stress and emotional dysfunctions that are attributed to neuromaladaptivebiobehaviors. To bring better understanding, we performed the integration of the clinical and pathophysiological components related to cardiology and psychosocial neuropsychology. Discussion: Stressful factors have been involved in CVD for a long time, and there has never been a methodology to objectively assess the neuropsychological clinic, in addition to the lack of integration of the various underlying and intricate pathophysiological mechanisms, which must be assessed for the strength of the causal effect through new population research. Conclusion: We present a clinical model with an approach to stressful effects through an unprecedented clinical approach to maladaptive biobehaviors, which involves objective assessment through clinical neuromarkers and enables a new organization of research and insights, in addition to the attempt to elucidate the origins of NCDs and MI.