Evaluations of the Bloch fitting method for the analysis of <scp>acidoCEST MRI</scp>

Although fixing Bloch fitting parameters with experimental measurements saved computation time, fixing these parameters did not significantly improve the accuracy or precision of measuring pH in phantoms or within in vivo tumors, Therefore, measurements of T<sub>1</sub>, T<sub>2</sub>, B<sub>1</sub>, and/or B<sub>0</sub> are not needed for acidoCEST MRI.

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Publication Details

Journal
Magnetic Resonance in Medicine
Published
2025-05-05
DOI
https://doi.org/10.1002/mrm.30511
Primary Topic
Lanthanide and Transition Metal Complexes
Type
article
Field-Weighted Citation Impact
0.00

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article

Evaluations of the Bloch fitting method for the analysis of acidoCEST MRI

Jorge de la Cerda, Franz Schuler, Aikaterini Kotrotsou, Tianzhe Li et al.
Magnetic Resonance in Medicine
Lanthanide and Transition Metal Complexes
article

Evaluations of the Bloch fitting method for the analysis of acidoCEST MRI

Jorge de la Cerda, Franz Schuler, Aikaterini Kotrotsou, Tianzhe Li, Priya N. Trakru, Shu Zhang, Richard Tran, Mark David Pagel, Kyle M. Jones
article en

Abstract

Although fixing Bloch fitting parameters with experimental measurements saved computation time, fixing these parameters did not significantly improve the accuracy or precision of measuring pH in phantoms or within in vivo tumors, Therefore, measurements of T<sub>1</sub>, T<sub>2</sub>, B<sub>1</sub>, and/or B<sub>0</sub> are not needed for acidoCEST MRI.

Magnetic Resonance in MedicineVol. 94(3)
The University of Texas MD Anderson Cancer Center (US), The University of Texas Health Science Center at Houston (US)
National Cancer Institute
Openalex Percentile: Top 94%
Lanthanide and Transition Metal Complexes
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