Designing 1,4-Dihydropyridines-Based Multitarget Therapeutics: Recent Advances and Future Directions

1,4-DHPs offer a promising framework for drug development, with the potential to address complex, multifactorial diseases. By understanding and optimizing SAR, medicinal chemists can design more selective and potent 1,4-DHP-based drugs. Future research should focus on refining these structural modifications to unlock their full therapeutic potential.

Authors

Institutions

Publication Details

Journal
Current Topics in Medicinal Chemistry
Published
2025-05-05
DOI
https://doi.org/10.2174/0115680266375345250414050338
Citations
1
Primary Topic
Multicomponent Synthesis of Heterocycles
Type
article
Field-Weighted Citation Impact
0.94
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Designing 1,4-Dihydropyridines-Based Multitarget Therapeutics: Recent Advances and Future Directions

Rajesh K. Singh, Monika Sharma, Aditi Soni
1 citations
Current Topics in Medicinal Chemistry
Multicomponent Synthesis of Heterocycles
0.94
article

Designing 1,4-Dihydropyridines-Based Multitarget Therapeutics: Recent Advances and Future Directions

Rajesh K. Singh, Monika Sharma, Aditi Soni
article en
1 citations

Abstract

1,4-DHPs offer a promising framework for drug development, with the potential to address complex, multifactorial diseases. By understanding and optimizing SAR, medicinal chemists can design more selective and potent 1,4-DHP-based drugs. Future research should focus on refining these structural modifications to unlock their full therapeutic potential.

Current Topics in Medicinal ChemistryVol. 25(19)
Hindu College of Pharmacy (IN), Punjab Technical University (IN)
Openalex Percentile: Top 26%
Multicomponent Synthesis of Heterocycles
0.94
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.