The Effects of Plasma Exosomes of Young Individuals Compared to Old Ones on Age-Related Inflammation and Lineage Differentiation of CD34 <sup>+</sup> Umbilical Cord Blood Hematopoietic Stem Cells
Our findings advocated the concept that circulating exosomes of old and young individuals may differently affect the pathways involved in the aging process in HSCs.Therefore, exosomes may be applied as therapeutic agents for regenerative medicine.
Authors
- Saeid Kaviani (ORCID: https://orcid.org/0000-0003-2213-8142)
- Shaban Alizadeh (ORCID: https://orcid.org/0000-0001-6253-0822)
- Mohammad Ahmadvand
- Maryam Helali (ORCID: https://orcid.org/0000-0001-6462-8364)
- Reza Afrisham (ORCID: https://orcid.org/0000-0001-8064-118X)
Institutions
- Tarbiat Modares University (IR)
- Iran University of Medical Sciences (IR)
- Tehran University of Medical Sciences (IR)
Publication Details
- Journal
- Current Topics in Medicinal Chemistry
- Published
- 2025-05-05
- DOI
- https://doi.org/10.2174/0115680266361607250418052405
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00