A detailed analysis of Spirulina's therapeutic properties in liver protection, oxidative stress reduction, and cancer management
Spirulina, a cyanobacterium recognized for its nutritional benefits, has recently garnered attention for its potential therapeutic properties. This review aims to comprehensively consolidate current knowledge on the pharmacological attributes of Spirulina species, focusing on their hepatoprotective, antioxidant and anticancer effects. An exhaustive literature search was conducted, collating data from empirical studies, clinical trials and reviews pertaining to the pharmacological effects of Spirulina. Spirulina exhibits significant hepatoprotective activities, evidenced by its ability to mitigate toxin-induced liver damage, primarily attributed to its rich antioxidant components (among others, phycocyanin, beta-carotene and tocopherol). These constituents counteract oxidative stress, making Spirulina a potent antioxidant agent. Additionally, numerous studies have pinpointed the anticancer potential of Spirulina. It impedes tumor growth and proliferation through various mechanisms, including the modulation of cell cycle, induction of apoptosis and inhibition of angiogenesis. Spirulina offers a trifecta of pharmacological benefits: hepatoprotection, antioxidant activity and anticancer properties. These findings underscore the need for further research and clinical trials to validate the therapeutic applications of Spirulina in modern medicine.
Authors
- Ali Mahmoud Al-Samydai (ORCID: https://orcid.org/0000-0003-0093-2310)
- Hany Akeel Al-Hussaniy
- Zahraa Salam Al-Tameemi (ORCID: https://orcid.org/0000-0002-0365-745X)
- Fuad A. Iraqi (ORCID: https://orcid.org/0000-0001-5525-206X)
- Meena Akeel Naji (ORCID: https://orcid.org/0009-0000-6823-2471)
- F. Naji (ORCID: https://orcid.org/0000-0002-7414-3376)
Institutions
- Al-Ahliyya Amman University (JO)
- Baghdad Medical City (IQ)
- Al-Nisour University College (IQ)
Publication Details
- Journal
- Current Issues in Pharmacy and Medical Sciences
- Published
- 2025-04-09
- DOI
- https://doi.org/10.12923/cipms-2025-0004
- Primary Topic
- Curcumin's Biomedical Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00