Intestinal Lipomatosis of the Ileum: A Rare Cause of Small Bowel Perforation

and deposition are usually limited to the submucosa but may also extend to the serosa and mesenteric adipose tissue (3) .The cause of fat deposition is unclear (4) .Intestinal lipomatosis does not show sex predominance and usually occurs after the fourth decade of life (5) .The most common Abstract zIntestinal lipomatosis is characterized by submucosal infiltration of mature adipose tissue, which is usually asymptomatic and can be detected incidentally.However, it may cause complications, such as intussusception, bleeding, and perforation.We describe a 12-year-old female patient who underwent surgery after the detection of intestinal perforation on abdominal computed tomography.Histopathologic examination of segmentary small bowel resection revealed a lesion predominantly located in the submucosa, occasionally causing atrophy in the muscle tissue and extending to the serosa.The lesion consisting of mature lipocytes was completely unencapsulated.Based on these findings, the patient was diagnosed with intestinal lipomatosis.Intestinal lipomatosis is usually asymptomatic and can be detected incidentally.However, it can lead to complications, such as intussusception, bleeding, and perforation, and these clinical conditions may be the first signs of the lesion, as in our case.

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Publication Details

Journal
The Anatolian Journal of General Medical Research
Published
2025-05-05
DOI
https://doi.org/10.4274/anatoljmed.2024.54254
Primary Topic
Gastrointestinal disorders and treatments
Type
article
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article

Intestinal Lipomatosis of the Ileum: A Rare Cause of Small Bowel Perforation

Halil Tanrıverdi, Hanife Seda Mavili, Peyker Temız, Semin Ayhan et al.
The Anatolian Journal of General Medical Research
Gastrointestinal disorders and treatments
article

Intestinal Lipomatosis of the Ileum: A Rare Cause of Small Bowel Perforation

Halil Tanrıverdi, Hanife Seda Mavili, Peyker Temız, Semin Ayhan, Ömer Atmış
article en

Abstract

and deposition are usually limited to the submucosa but may also extend to the serosa and mesenteric adipose tissue (3) .The cause of fat deposition is unclear (4) .Intestinal lipomatosis does not show sex predominance and usually occurs after the fourth decade of life (5) .The most common Abstract zIntestinal lipomatosis is characterized by submucosal infiltration of mature adipose tissue, which is usually asymptomatic and can be detected incidentally.However, it may cause complications, such as intussusception, bleeding, and perforation.We describe a 12-year-old female patient who underwent surgery after the detection of intestinal perforation on abdominal computed tomography.Histopathologic examination of segmentary small bowel resection revealed a lesion predominantly located in the submucosa, occasionally causing atrophy in the muscle tissue and extending to the serosa.The lesion consisting of mature lipocytes was completely unencapsulated.Based on these findings, the patient was diagnosed with intestinal lipomatosis.Intestinal lipomatosis is usually asymptomatic and can be detected incidentally.However, it can lead to complications, such as intussusception, bleeding, and perforation, and these clinical conditions may be the first signs of the lesion, as in our case.

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Intestinal Lipomatosis of the Ileum: A Rare Cause of Small Bowel Perforation — Halil Tanrıverdi, Hanife Seda Mavili, et al. · The Anatolian Journal of General Medical Research (2025) | TGRS Research Map | TGRS