A Split Renal Function–Based Approach for Predicting New Baseline Glomerular Filtration Rate After Radical Nephroureterectomy
PVA<sup>+</sup> incorporates both differential renal function (degree of enhancement) and parenchymal volumes and outperforms other SRF-based and non-SRF-based approaches for predicting NBGFR after RNU. These findings alleviate concerns that the prevalence of hydronephrosis and IRMs in this population reduces accuracy of SRF-based approaches. PVA<sup>+</sup> can inform counseling about the timing of systemic chemotherapy in patients with high-risk UTUC.
Authors
- Nicholas Heller (ORCID: https://orcid.org/0000-0001-8516-8707)
- Nityam Rathi (ORCID: https://orcid.org/0000-0002-6718-8170)
- Rebecca A. Campbell (ORCID: https://orcid.org/0000-0003-0969-6422)
- Steven C. Campbell (ORCID: https://orcid.org/0000-0002-9110-0343)
- Angelica Bartholomew (ORCID: https://orcid.org/0009-0001-7362-8750)
- Kieran Lewis (ORCID: https://orcid.org/0000-0002-0342-7902)
- Carlos Muñoz-López (ORCID: https://orcid.org/0000-0002-1299-823X)
- Nima Almassi (ORCID: https://orcid.org/0000-0002-6307-9268)
- Robert Abouassaly (ORCID: https://orcid.org/0000-0001-6897-6518)
- Akira Kazama (ORCID: https://orcid.org/0000-0002-8354-6388)
- Samuel Haywood (ORCID: https://orcid.org/0000-0002-6003-0266)
- Christopher Weight (ORCID: https://orcid.org/0000-0001-9381-959X)
- Jason Scovell
- Anne Wong
- Jayant Siva
- Eran Maina
Institutions
- Cleveland Clinic (US)
- Niigata University (JP)
Publication Details
- Journal
- Urology Practice
- Published
- 2025-05-05
- DOI
- https://doi.org/10.1097/upj.0000000000000826
- Primary Topic
- Renal cell carcinoma treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00