Bullous Varicella in an Immunocompetent Adult: A Case Report

Chickenpox is a common viral infection that usually runs a benign course. Bullous varicella is an atypical presentation of chickenpox, which is usually seen in immunocompromised individuals. We describe a 54-year-old immunocompetent woman who presented to the emergency room with a 10-day history of fever and painful, fluid-filled lesions on her face, trunk, and extremities. Upon examination, the face, trunk, and extremities showed many vesicles, pustules, and bullae over an erythematous base. Multinucleated giant cells (MNGs) with acantholytic cells were visible in the Tzanck smear. A diagnosis of bullous varicella was made based on the appearance of the lesions and the results of the Tzanck smear. The patient was treated with intravenous acyclovir and antibiotics. We report this case due to the rarity of bullous varicella in immunocompetent adults.

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Journal
Cureus
Published
2025-05-05
DOI
https://doi.org/10.7759/cureus.83510
Primary Topic
Herpesvirus Infections and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Bullous Varicella in an Immunocompetent Adult: A Case Report

Murugan Sundaram, Anuradha Priyadarshini, A.P. Vignesh, Varsha R Parupati et al.
Cureus
Herpesvirus Infections and Treatments
article

Bullous Varicella in an Immunocompetent Adult: A Case Report

Murugan Sundaram, Anuradha Priyadarshini, A.P. Vignesh, Varsha R Parupati, Dr Adikrishnan Swaminathan
article en

Abstract

Chickenpox is a common viral infection that usually runs a benign course. Bullous varicella is an atypical presentation of chickenpox, which is usually seen in immunocompromised individuals. We describe a 54-year-old immunocompetent woman who presented to the emergency room with a 10-day history of fever and painful, fluid-filled lesions on her face, trunk, and extremities. Upon examination, the face, trunk, and extremities showed many vesicles, pustules, and bullae over an erythematous base. Multinucleated giant cells (MNGs) with acantholytic cells were visible in the Tzanck smear. A diagnosis of bullous varicella was made based on the appearance of the lesions and the results of the Tzanck smear. The patient was treated with intravenous acyclovir and antibiotics. We report this case due to the rarity of bullous varicella in immunocompetent adults.

CureusVol. 17(5)
Sri Ramachandra Institute of Higher Education and Research (IN)
Openalex Percentile: Top 86%
Herpesvirus Infections and Treatments
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