Prognostic Value of Tumor Regression Grade After Chemotherapy Versus Chemoradiotherapy in Patients Undergoing Neoadjuvant Treatment for Locally Advanced Esophageal Adenocarcinoma

Tumor regression grade was significantly associated with survival after NACT, but not with NACRT. Despite a lower rate of pCR, both OS and, especially, DFS of patients with pCR improved after NACT compared with NACRT.

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Publication Details

Journal
Annals of Surgical Oncology
Published
2025-05-05
DOI
https://doi.org/10.1245/s10434-025-17264-2
Citations
3
Primary Topic
Esophageal Cancer Research and Treatment
Type
article
Field-Weighted Citation Impact
6.02

Funders

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article

Prognostic Value of Tumor Regression Grade After Chemotherapy Versus Chemoradiotherapy in Patients Undergoing Neoadjuvant Treatment for Locally Advanced Esophageal Adenocarcinoma

Maria Elisa Sciuto, Renato Salvador, Lucia Moletta, Simone Giacopuzzi et al.
3 citations
Annals of Surgical Oncology
Esophageal Cancer Research and Treatment
6.02
article

Prognostic Value of Tumor Regression Grade After Chemotherapy Versus Chemoradiotherapy in Patients Undergoing Neoadjuvant Treatment for Locally Advanced Esophageal Adenocarcinoma

Maria Elisa Sciuto, Renato Salvador, Lucia Moletta, Simone Giacopuzzi, Giovanni Capovilla, Peter Grimminger, Jacopo Weindelmayer, Evangelos Tagkalos, Sara Lonardi, Michele Valmasoni, Gianpietro Zanchettin, Giovanni De Manzoni, Sara Galuppo, Cecilia Turolo, Carlo Alberto De Pasqual, Felix Berlth, Eren Uzun, Elisa Sefora Pierobon, Federica Riccio, Alessia Scarton, Luca Provenzano
article en
3 citations

Abstract

Tumor regression grade was significantly associated with survival after NACT, but not with NACRT. Despite a lower rate of pCR, both OS and, especially, DFS of patients with pCR improved after NACT compared with NACRT.

Annals of Surgical OncologyVol. 32(8)
University of Verona (IT), University of Padua (IT), Johannes Gutenberg University Mainz (DE), University Medical Center of the Johannes Gutenberg University Mainz (DE), Universitätsklinikum Tübingen (DE), Istituto Oncologico Veneto (IT)
Università degli Studi di Padova
Good health and well-being
Openalex Percentile: Top 4%
Esophageal Cancer Research and Treatment
6.02
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