Prognostic Value of Tumor Regression Grade After Chemotherapy Versus Chemoradiotherapy in Patients Undergoing Neoadjuvant Treatment for Locally Advanced Esophageal Adenocarcinoma
Tumor regression grade was significantly associated with survival after NACT, but not with NACRT. Despite a lower rate of pCR, both OS and, especially, DFS of patients with pCR improved after NACT compared with NACRT.
Authors
- Maria Elisa Sciuto
- Renato Salvador (ORCID: https://orcid.org/0000-0002-3281-0361)
- Lucia Moletta (ORCID: https://orcid.org/0000-0003-4041-5721)
- Simone Giacopuzzi
- Giovanni Capovilla (ORCID: https://orcid.org/0000-0002-2271-7745)
- Peter Grimminger (ORCID: https://orcid.org/0000-0002-1859-9213)
- Jacopo Weindelmayer (ORCID: https://orcid.org/0000-0002-9859-6038)
- Evangelos Tagkalos (ORCID: https://orcid.org/0000-0001-7888-4959)
- Sara Lonardi (ORCID: https://orcid.org/0000-0002-7593-8138)
- Michele Valmasoni (ORCID: https://orcid.org/0000-0002-1462-8275)
- Gianpietro Zanchettin
- Giovanni De Manzoni (ORCID: https://orcid.org/0000-0002-6787-164X)
- Sara Galuppo (ORCID: https://orcid.org/0000-0002-2290-9157)
- Cecilia Turolo
- Carlo Alberto De Pasqual (ORCID: https://orcid.org/0000-0001-7719-258X)
- Felix Berlth (ORCID: https://orcid.org/0000-0002-3780-0728)
- Eren Uzun
- Elisa Sefora Pierobon (ORCID: https://orcid.org/0000-0002-5836-1197)
- Federica Riccio (ORCID: https://orcid.org/0009-0008-7739-3304)
- Alessia Scarton (ORCID: https://orcid.org/0000-0001-7309-2573)
- Luca Provenzano (ORCID: https://orcid.org/0000-0002-4596-444X)
Institutions
- University of Verona (IT)
- University of Padua (IT)
- Johannes Gutenberg University Mainz (DE)
- University Medical Center of the Johannes Gutenberg University Mainz (DE)
- Universitätsklinikum Tübingen (DE)
- Istituto Oncologico Veneto (IT)
Publication Details
- Journal
- Annals of Surgical Oncology
- Published
- 2025-05-05
- DOI
- https://doi.org/10.1245/s10434-025-17264-2
- Citations
- 3
- Primary Topic
- Esophageal Cancer Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 6.02
Funders
- Università degli Studi di Padova