Contribution of Leukocidin ED to the Pathogenesis of <i>Staphylococcus aureus</i> Endophthalmitis
LukED does not seem to be essential for the pathogenesis of experimental S. aureus endophthalmitis. However, other leukotoxins are expressed in vivo, which may compensate for the effects of LukED during infection.
Authors
- Roger Astley (ORCID: https://orcid.org/0000-0002-2243-119X)
- Yan Chen (ORCID: https://orcid.org/0000-0002-7679-1713)
- Phillip S. Coburn (ORCID: https://orcid.org/0000-0003-3799-5251)
- Michelle C. Callegan (ORCID: https://orcid.org/0000-0002-1400-8586)
- Luis Longoria-Gonzalez
Institutions
- Dean McGee Eye Institute (US)
- University of Oklahoma Health Sciences Center (US)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2025-05-05
- DOI
- https://doi.org/10.1167/iovs.66.5.11
- Primary Topic
- Ocular Infections and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Research to Prevent Blindness
- National Institutes of Health
- University of Oklahoma Health Sciences Center
- National Institute of Allergy and Infectious Diseases