The effects of oral supplementation of carvacrol on autophagy and epithelial to mesenchymal transition regulation in UV-induced skin damage

Based on our results, it can be concluded that CVC may prevent autophagic cell death by suppressing autophagy and it might support the wound healing process by inducing EMT in UV-induced skin damage. The molecular mechanisms of the effect of CVC on autophagy and EMT mechanisms should be clarified in further studies.

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Publication Details

Journal
Cutaneous and Ocular Toxicology
Published
2025-04-03
DOI
https://doi.org/10.1080/15569527.2025.2496636
Primary Topic
Sirtuins and Resveratrol in Medicine
Type
article
Field-Weighted Citation Impact
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article

The effects of oral supplementation of carvacrol on autophagy and epithelial to mesenchymal transition regulation in UV-induced skin damage

Sakine Akar, Gülşah Evyapan, Hatice Uce Özkol, Fikret Altındağ et al.
1 links
Cutaneous and Ocular Toxicology
Sirtuins and Resveratrol in Medicine
article

The effects of oral supplementation of carvacrol on autophagy and epithelial to mesenchymal transition regulation in UV-induced skin damage

Sakine Akar, Gülşah Evyapan, Hatice Uce Özkol, Fikret Altındağ, Halil Özkol, Özge Alvur
article en

Abstract

Based on our results, it can be concluded that CVC may prevent autophagic cell death by suppressing autophagy and it might support the wound healing process by inducing EMT in UV-induced skin damage. The molecular mechanisms of the effect of CVC on autophagy and EMT mechanisms should be clarified in further studies.

Cutaneous and Ocular ToxicologyVol. 44(2)
Van Yüzüncü Yıl Üniversitesi (TR)
Zero hunger
Openalex Percentile: Top 89%
Sirtuins and Resveratrol in Medicine
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