A Serendipitous Histopathological Revelation: An Intriguing Case Report of a Cystic Schwannoma of the Lateral Neck

Schwannomas are rare, benign tumors that arise from Schwann cells, which produce the myelin sheath around peripheral nerves. Cystic degeneration is an uncommon feature of schwannomas, occurring in approximately 4% of cases. The diagnosis of cystic schwannomas can be challenging due to their rarity and nonspecific clinical and radiological features. A 45-year-old female presented with a two-year history of a gradually enlarging neck mass, which was initially suspected to be a branchial cleft cyst. Computed tomography (CT) scans showed a well-defined cystic lesion in the left supraclavicular region. The patient underwent ultrasound-guided fine-needle aspiration cytology (FNAC), which yielded hypocellular fluid. The patient underwent surgical excision of the mass, which was subsequently diagnosed as a cystic schwannoma based on histopathological examination. Cystic schwannomas can pose a diagnostic challenge due to their rarity and nonspecific clinical and radiological features. Awareness of the clinical and pathological features of cystic schwannomas is essential for timely diagnosis and effective treatment. Accurate diagnosis is crucial to ensure optimal management and prevent recurrence.

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Publication Details

Journal
Cureus
Published
2025-05-05
DOI
https://doi.org/10.7759/cureus.83515
Primary Topic
Neurofibromatosis and Schwannoma Cases
Type
article
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article

A Serendipitous Histopathological Revelation: An Intriguing Case Report of a Cystic Schwannoma of the Lateral Neck

Ravindran Chirukandath, Saranya Sasidharan, Hisashi Anan, Arjun Nair et al.
Cureus
Neurofibromatosis and Schwannoma Cases
article

A Serendipitous Histopathological Revelation: An Intriguing Case Report of a Cystic Schwannoma of the Lateral Neck

Ravindran Chirukandath, Saranya Sasidharan, Hisashi Anan, Arjun Nair, Tinu Sasi
article en

Abstract

Schwannomas are rare, benign tumors that arise from Schwann cells, which produce the myelin sheath around peripheral nerves. Cystic degeneration is an uncommon feature of schwannomas, occurring in approximately 4% of cases. The diagnosis of cystic schwannomas can be challenging due to their rarity and nonspecific clinical and radiological features. A 45-year-old female presented with a two-year history of a gradually enlarging neck mass, which was initially suspected to be a branchial cleft cyst. Computed tomography (CT) scans showed a well-defined cystic lesion in the left supraclavicular region. The patient underwent ultrasound-guided fine-needle aspiration cytology (FNAC), which yielded hypocellular fluid. The patient underwent surgical excision of the mass, which was subsequently diagnosed as a cystic schwannoma based on histopathological examination. Cystic schwannomas can pose a diagnostic challenge due to their rarity and nonspecific clinical and radiological features. Awareness of the clinical and pathological features of cystic schwannomas is essential for timely diagnosis and effective treatment. Accurate diagnosis is crucial to ensure optimal management and prevent recurrence.

CureusVol. 17(5)
Government Medical College (IN)
Openalex Percentile: Top 84%
Neurofibromatosis and Schwannoma Cases
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A Serendipitous Histopathological Revelation: An Intriguing Case Report of a Cystic Schwannoma of the Lateral Neck — Ravindran Chirukandath, Saranya Sasidharan, et al. · Cureus (2025) | TGRS Research Map | TGRS