Threshold analysis of mortality outcomes in the collaborative ocular melanoma study (COMS)
The COMS trial did not reveal a clinically meaningful survival difference. Our findings underscore the substantial mortality shifts required for statistical significance and highlight the challenges in detecting modest treatment effects in uveal melanoma trials.
Authors
- Viktor Gill (ORCID: https://orcid.org/0000-0003-1233-3366)
- Gustav Stålhammar (ORCID: https://orcid.org/0000-0001-9401-8911)
- Shiva Sabazade (ORCID: https://orcid.org/0000-0003-2533-3103)
Institutions
- Karolinska Institutet (SE)
- Västmanlands sjukhus Västerås (SE)
- S:t Eriks Ögonsjukhus (SE)
Publication Details
- Journal
- Melanoma Management
- Published
- 2025-05-05
- DOI
- https://doi.org/10.1080/20450885.2025.2494977
- Primary Topic
- Ocular Oncology and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00