Prehospital Trauma Compendium: Tranexamic Acid in Trauma – A Joint Position Statement and Resource Document of NAEMSP, ACEP, and ACS-COT

Prehospital use of tranexamic acid (TXA) has grown substantially over the past decade despite contradictory evidence supporting its widespread use. Since the previous guidance document on the prehospital use of TXA for injured patients was published by the National Association of Emergency Medical Services Physicians (NAEMSP), the American College of Surgeons Committee on Trauma (ACS-COT), and the American College of Emergency Physicians (ACEP) in 2016, new research has investigated outcomes of patients who receive TXA in the prehospital setting. To provide updated evidence-based guidance on the use of intravenous TXA for injured patients in the EMS setting, we performed a structured literature review and developed the following recommendations supported by the evidence summarized in the accompanying resource document.

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Publication Details

Journal
Prehospital Emergency Care
Published
2025-05-05
DOI
https://doi.org/10.1080/10903127.2025.2497056
Citations
1
Primary Topic
Trauma, Hemostasis, Coagulopathy, Resuscitation
Type
article
Field-Weighted Citation Impact
1.55
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article

Prehospital Trauma Compendium: Tranexamic Acid in Trauma – A Joint Position Statement and Resource Document of NAEMSP, ACEP, and ACS-COT

Jeffrey M. Goodloe, Eric M. Campion, John W. Lyng, Whitney Barrett et al.
1 citations
Prehospital Emergency Care
Trauma, Hemostasis, Coagulopathy, Resuscitation
1.55
article

Prehospital Trauma Compendium: Tranexamic Acid in Trauma – A Joint Position Statement and Resource Document of NAEMSP, ACEP, and ACS-COT

Jeffrey M. Goodloe, Eric M. Campion, John W. Lyng, Whitney Barrett, Kevin A. Kaucher, Peter Fischer, Christopher B. Colwell, Ross E Orpet
article en
1 citations

Abstract

Prehospital use of tranexamic acid (TXA) has grown substantially over the past decade despite contradictory evidence supporting its widespread use. Since the previous guidance document on the prehospital use of TXA for injured patients was published by the National Association of Emergency Medical Services Physicians (NAEMSP), the American College of Surgeons Committee on Trauma (ACS-COT), and the American College of Emergency Physicians (ACEP) in 2016, new research has investigated outcomes of patients who receive TXA in the prehospital setting. To provide updated evidence-based guidance on the use of intravenous TXA for injured patients in the EMS setting, we performed a structured literature review and developed the following recommendations supported by the evidence summarized in the accompanying resource document.

Prehospital Emergency Care
University of Tennessee Health Science Center (US), University of New Mexico (US), University of California, San Francisco (US), Denver Health Medical Center (US), American College of Physicians (US), National Environmental Health Association (US), Regional Health (US), North Memorial Health Care (US), National Association of EMS Physicians (US), Dermatology Specialists (US), American College of Emergency Physicians (US), University of Oklahoma (US), University of Colorado Denver (US), American College of Surgeons (US)
Openalex Percentile: Top 20%
Trauma, Hemostasis, Coagulopathy, Resuscitation
1.55
DOISourceOpenAlex
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