The Formulation of Herbal Nanogel for Wound Healing Using Clitoria Ternatea

The present study focuses on the formulation and evaluation of a nano-gel incorporating the plant extract of Clitoria ternatea (Butterfly Pea) for enhanced wound healing and antimicrobial activity. Clitoria ternatea is a well-known medicinal plant rich in bioactive compounds such as flavonoids, anthocyanins, and saponins, which possess significant antioxidant, antiinflammatory, and antimicrobial properties. In this project, the ethanolic extract of Clitoria ternatea was utilized due to its enhanced solubility and stability. The nano-gel was formulated using Carbopol as the gelling agent, along with appropriate stabilizers and preservatives to ensure long-term stability. The prepared formulation was evaluated for physicochemical parameters, including pH, viscosity, spread ability, and drug release profile. Antimicrobial activity was assessed against common wound-infecting pathogens such as Staphylococcus aureus and Escherichia coli. The formulation demonstrated improved skin penetration, rapid wound contraction, and enhanced collagen synthesis, indicating superior therapeutic effect

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Publication Details

Journal
International Journal for Research in Applied Science and Engineering Technology
Published
2025-05-05
DOI
https://doi.org/10.22214/ijraset.2025.70124
Primary Topic
Medicinal Plant Research
Type
article
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article

The Formulation of Herbal Nanogel for Wound Healing Using Clitoria Ternatea

Bhagyshree Mote
1 links
International Journal for Research in Applied Science and Engineering Technology
Medicinal Plant Research
article

The Formulation of Herbal Nanogel for Wound Healing Using Clitoria Ternatea

Bhagyshree Mote
article en

Abstract

The present study focuses on the formulation and evaluation of a nano-gel incorporating the plant extract of Clitoria ternatea (Butterfly Pea) for enhanced wound healing and antimicrobial activity. Clitoria ternatea is a well-known medicinal plant rich in bioactive compounds such as flavonoids, anthocyanins, and saponins, which possess significant antioxidant, antiinflammatory, and antimicrobial properties. In this project, the ethanolic extract of Clitoria ternatea was utilized due to its enhanced solubility and stability. The nano-gel was formulated using Carbopol as the gelling agent, along with appropriate stabilizers and preservatives to ensure long-term stability. The prepared formulation was evaluated for physicochemical parameters, including pH, viscosity, spread ability, and drug release profile. Antimicrobial activity was assessed against common wound-infecting pathogens such as Staphylococcus aureus and Escherichia coli. The formulation demonstrated improved skin penetration, rapid wound contraction, and enhanced collagen synthesis, indicating superior therapeutic effect

International Journal for Research in Applied Science and Engineering TechnologyVol. 13(5)
Openalex Percentile: Top 93%
Medicinal Plant Research
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