The Interplay of Dietary Choline and Methyl Donors in Modulating Maternal Inflammation: Insights from Project Viva
These findings highlight the interplay between choline and other dietary methyl donors in modulating inflammation status during pregnancy, specifically through IL-6. Higher intake of methyl donor nutrients may be necessary for any anti-inflammatory effects of choline, although further studies in this area are warranted.
Authors
- Elisabeth Anne Larson (ORCID: https://orcid.org/0000-0002-9605-4710)
- Wei Perng (ORCID: https://orcid.org/0000-0001-8552-6850)
- Laura E. Smith (ORCID: https://orcid.org/0000-0002-0164-9827)
- Karen M Switkowski (ORCID: https://orcid.org/0000-0001-8212-4354)
- Emily Oken (ORCID: https://orcid.org/0000-0003-2513-3339)
- Sheryl L. Rifas‐Shiman
Institutions
- Harvard University (US)
- Colorado School of Public Health (US)
- Cornell University (US)
- Harvard Pilgrim Health Care (US)
- Zvitambo Institute for Maternal and Child Health Research (ZW)
Publication Details
- Journal
- Journal of Nutrition
- Published
- 2025-05-05
- DOI
- https://doi.org/10.1016/j.tjnut.2025.04.032
- Primary Topic
- Birth, Development, and Health
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health
- National Institute of Environmental Health Sciences
- Eunice Kennedy Shriver National Institute of Child Health and Human Development