Jujuboside A improves insomnia by maintaining mitochondrial homeostasis in prefrontal neurons
JB-A can improve insomnia by restoring mitochondrial intracellular oxidative phosphorylation, regulating mPTP to maintain mitochondrial homeostasis, and alleviating structural damage, providing a scientific basis for finding new targets for insomnia treatment.
Authors
- Zhen Zhang (ORCID: https://orcid.org/0000-0001-6710-9826)
- Gongxin Chen
- Xianwei Che (ORCID: https://orcid.org/0000-0002-0039-7306)
- Tingyu Feng
- Chunmei Ma (ORCID: https://orcid.org/0000-0002-3173-9778)
- Xiaowu Xu
- Jingying Chen (ORCID: https://orcid.org/0000-0002-2479-818X)
- Wenping Guo (ORCID: https://orcid.org/0000-0003-3129-178X)
- Zou Juntao
- Haozhe Yuan (ORCID: https://orcid.org/0009-0009-8279-4230)
Institutions
- Guangzhou University of Chinese Medicine (CN)
- Sun Yat-sen University (CN)
- New York College of Traditional Chinese Medicine (US)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Brain Research Bulletin
- Published
- 2025-05-05
- DOI
- https://doi.org/10.1016/j.brainresbull.2025.111372
- Citations
- 3
- Primary Topic
- Sleep and Wakefulness Research
- Type
- article
- Field-Weighted Citation Impact
- 4.29