Cemiplimab monotherapy as first‐line treatment of patients with brain metastases from advanced non–small cell lung cancer with programmed cell death‐ligand 1 ≥50%

In patients with advanced NSCLC with PD-L1 ≥50%, first-line cemiplimab monotherapy improved survival and patient-reported outcomes over chemotherapy for those who received prior radiotherapy for symptomatic brain metastases.

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Institutions

Publication Details

Journal
Cancer
Published
2025-05-05
DOI
https://doi.org/10.1002/cncr.35864
Citations
4
Primary Topic
Lung Cancer Treatments and Mutations
Type
article
Field-Weighted Citation Impact
6.07

Funders

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article

Cemiplimab monotherapy as first‐line treatment of patients with brain metastases from advanced non–small cell lung cancer with programmed cell death‐ligand 1 ≥50%

Mahmut Gümüş, Igor Bondarenko, Frank Seebach, Mustafa Özgüroğlu et al.
4 citations
Cancer
Lung Cancer Treatments and Mutations
6.07
article

Cemiplimab monotherapy as first‐line treatment of patients with brain metastases from advanced non–small cell lung cancer with programmed cell death‐ligand 1 ≥50%

Mahmut Gümüş, Igor Bondarenko, Frank Seebach, Mustafa Özgüroğlu, Miranda Gogishvili, Saadettin Kılıçkap, J-F. Pouliot, Dmitry Bentsion, Jennifer McGinniss, İrfan Çiçin, Oleg Gladkov, Virote Sriuranpong, Hacı Mehmet Türk, Petra Rietschel, Ruben G.W. Quek, Ahmet Sezer, Giuseppe Gullo, Xuanyao He, D. McIntyre
article en
4 citations

Abstract

In patients with advanced NSCLC with PD-L1 ≥50%, first-line cemiplimab monotherapy improved survival and patient-reported outcomes over chemotherapy for those who received prior radiotherapy for symptomatic brain metastases.

CancerVol. 131(10)
Chulalongkorn University (TH), Regeneron (United States) (US), Başkent University (TR), King Chulalongkorn Memorial Hospital (TH), Bezmiâlem Vakıf Üniversitesi (TR), Istanbul University-Cerrahpaşa (TR), Istinye University (TR), Ulyanovsk Regional Oncology Center (RU), Istanbul Medeniyet University (TR), Dnipro State Medical University (UA)
Sanofi, Regeneron Pharmaceuticals
Good health and well-being
Openalex Percentile: Top 4%
Lung Cancer Treatments and Mutations
6.07
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Cemiplimab monotherapy as first‐line treatment of patients with brain metastases from advanced non–small cell lung cancer with programmed cell death‐ligand 1 ≥50% — Mahmut Gümüş, Igor Bondarenko, et al. · Cancer (2025) | TGRS Research Map | TGRS