Successful Resolution of Hyaluronic Acid Embolism Using Ultrasound-guided Intravascular Hyaluronidase Injection

The accidental introduction of hyaluronic acid into blood vessels during injection may result in vascular embolism. Such blockages may obstruct blood flow to specific areas, leading to tissue ischemia, hypoxia, and potentially severe complications such as skin and tissue necrosis. This report presents the case of a 35-year-old woman who experienced an embolism following a nasolabial hyaluronic acid injection, which was successfully treated with intravascular hyaluronidase injection guided by ultrasound techniques. Utilizing ultrasound technology, the embolized vessel was precisely located, allowing for the effective administration of intravascular hyaluronidase injection for dissolution. Ultrasonography aids clinicians in enhancing their understanding of patients with embolic conditions by accurately determining the extent and severity of vascular embolization, thereby enabling more precise treatment strategies.

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Publication Details

Journal
Journal of Craniofacial Surgery
Published
2025-05-05
DOI
https://doi.org/10.1097/scs.0000000000011415
Citations
1
Primary Topic
Facial Rejuvenation and Surgery Techniques
Type
article
Field-Weighted Citation Impact
2.00
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article

Successful Resolution of Hyaluronic Acid Embolism Using Ultrasound-guided Intravascular Hyaluronidase Injection

Jintian Hu, Fengfeng Guo, Hongli Chai, Yutong Liang
1 citations
Journal of Craniofacial Surgery
Facial Rejuvenation and Surgery Techniques
2.00
article

Successful Resolution of Hyaluronic Acid Embolism Using Ultrasound-guided Intravascular Hyaluronidase Injection

Jintian Hu, Fengfeng Guo, Hongli Chai, Yutong Liang
article en
1 citations

Abstract

The accidental introduction of hyaluronic acid into blood vessels during injection may result in vascular embolism. Such blockages may obstruct blood flow to specific areas, leading to tissue ischemia, hypoxia, and potentially severe complications such as skin and tissue necrosis. This report presents the case of a 35-year-old woman who experienced an embolism following a nasolabial hyaluronic acid injection, which was successfully treated with intravascular hyaluronidase injection guided by ultrasound techniques. Utilizing ultrasound technology, the embolized vessel was precisely located, allowing for the effective administration of intravascular hyaluronidase injection for dissolution. Ultrasonography aids clinicians in enhancing their understanding of patients with embolic conditions by accurately determining the extent and severity of vascular embolization, thereby enabling more precise treatment strategies.

Journal of Craniofacial SurgeryVol. 37(1/2)
Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
Good health and well-being
Openalex Percentile: Top 15%
Facial Rejuvenation and Surgery Techniques
2.00
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Successful Resolution of Hyaluronic Acid Embolism Using Ultrasound-guided Intravascular Hyaluronidase Injection — Jintian Hu, Fengfeng Guo, et al. · Journal of Craniofacial Surgery (2025) | TGRS Research Map | TGRS