Development of an LC-MS method for the determination of simvastatin and its hydroxy acid form in muscle tissue and method application

The obtained results proved that the method may be a useful tool for explaining muscle effects related to statin therapy.

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Publication Details

Journal
PLoS ONE
Published
2025-05-05
DOI
https://doi.org/10.1371/journal.pone.0322808
Primary Topic
Lipoproteins and Cardiovascular Health
Type
article
Field-Weighted Citation Impact
0.00

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article

Development of an LC-MS method for the determination of simvastatin and its hydroxy acid form in muscle tissue and method application

Karolina Pietrowska, Michał Ciborowski, Steen Larsen, Emilia Fornal et al.
PLoS ONE
Lipoproteins and Cardiovascular Health
article

Development of an LC-MS method for the determination of simvastatin and its hydroxy acid form in muscle tissue and method application

Karolina Pietrowska, Michał Ciborowski, Steen Larsen, Emilia Fornal, Ewa Paszkowska
article en

Abstract

The obtained results proved that the method may be a useful tool for explaining muscle effects related to statin therapy.

PLoS ONEVol. 20(5)
Medical University of Lublin (PL), University of Copenhagen (DK), Medical University of Białystok (PL)
Narodowym Centrum Nauki
Good health and well-being
Openalex Percentile: Top 83%
Lipoproteins and Cardiovascular Health
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