Elevated urine albumin-to-creatinine ratio as a risk factor for cognitive impairment in older adults: A cross-sectional analysis of NHANES data

This study highlights the significant association between elevated UACR and cognitive impairment in older adults. Notably, even at lower UACR levels, increases in UACR are associated with a higher risk of cognitive impairment. These findings underscore the importance of incorporating kidney health management into strategies aimed at preventing cognitive decline. Further longitudinal studies are needed to clarify the causal relationship and explore interventions targeting UACR to preserve cognitive function.