Neurological, functional, and quality of life outcomes following combined mesenchymal stem cell and Schwann cell therapy in spinal cord injury: a 9-year experience
This study demonstrates significant neurological, functional, and quality of life improvements following combined cell therapy with autologous MSCs and SCs in patients with complete SCI. Future research should investigate potential synergies with other therapies and conduct comparative efficacy analyses.
Authors
- Melika Hosseinpour
- Ida Mohammadi (ORCID: https://orcid.org/0000-0002-0662-0329)
- Saeed Oraee‐Yazdani (ORCID: https://orcid.org/0000-0003-4550-9698)
- Maryam Golmohammadi (ORCID: https://orcid.org/0000-0003-3225-9044)
- Roozbeh Tavanaei (ORCID: https://orcid.org/0000-0002-2932-3132)
- Mohammadhosein Akhlaghpasand (ORCID: https://orcid.org/0000-0001-7514-5931)
- Bardia Hajikarimloo (ORCID: https://orcid.org/0000-0001-8801-1158)
- Alireza Zali (ORCID: https://orcid.org/0000-0002-2298-2290)
- Kaveh Oraii Yazdani (ORCID: https://orcid.org/0000-0002-7810-8092)
- Amir Ghaffari Jolfayi (ORCID: https://orcid.org/0000-0002-9223-5565)
- Maede Hosseinpoor
Institutions
- Iran University of Medical Sciences (IR)
- Stem Cell Technology Research Center (IR)
- Shahid Beheshti University of Medical Sciences (IR)
Publication Details
- Journal
- Stem Cell Research & Therapy
- Published
- 2025-05-05
- DOI
- https://doi.org/10.1186/s13287-025-04312-7
- Citations
- 2
- Primary Topic
- Spinal Cord Injury Research
- Type
- article
- Field-Weighted Citation Impact
- 2.94
Funders
- Shahid Beheshti University of Medical Sciences