Viral dynamics and factors associated with duration of COVID-19 positivity: evidence from the first-three epidemiological waves in Cameroon
A median positivity duration of 15 days is in accordance with viral clearance around 2 weeks for optimal confinement at community-level. Men and/or the elderly stand at higher risk of prolonged infection. Given the viral decay (0.3 Ct daily), we suggest personalized confinement periods. The variability of positivity duration according to waves could be function of strains which could be a factor influencing positivity duration.
Authors
- Grâce Beloumou (ORCID: https://orcid.org/0000-0002-6870-7366)
- Nadine Fainguem (ORCID: https://orcid.org/0000-0002-8497-7948)
- Sandrine Claire Djupsa Ndjeyep
- Alfred K. Njamnshi (ORCID: https://orcid.org/0000-0003-0052-1511)
- John Otshudiema Otokoye
- Alex Durand Nka (ORCID: https://orcid.org/0000-0002-9358-8661)
- Maria Mercedes Santoro (ORCID: https://orcid.org/0000-0002-6228-1114)
- Yap Boum (ORCID: https://orcid.org/0000-0002-6823-8539)
- Evariste Molimbou
- Ezéchiel Ngoufack Jagni Semengue (ORCID: https://orcid.org/0000-0001-8768-2371)
- Luna Colagrossi (ORCID: https://orcid.org/0000-0001-5618-1523)
- Alexis Ndjolo (ORCID: https://orcid.org/0000-0002-4951-9271)
- Nicaise Ndembi (ORCID: https://orcid.org/0000-0001-5131-3136)
- Edie Gregory Halle Ekane
- Yagaï Bouba (ORCID: https://orcid.org/0000-0002-4187-683X)
- Claudia Alteri (ORCID: https://orcid.org/0000-0003-4270-5079)
- Aissatou Abba (ORCID: https://orcid.org/0000-0002-1625-2152)
- Francesca Ceccherini‐Silberstein (ORCID: https://orcid.org/0000-0002-6024-5101)
- Aurelie Minelle Kengni Ngueko (ORCID: https://orcid.org/0000-0002-0733-5730)
- Naomi-Karell Etame (ORCID: https://orcid.org/0009-0004-4320-0982)
- Joseph Fokam (ORCID: https://orcid.org/0000-0002-1501-2763)
- Collins Ambe Chenwi (ORCID: https://orcid.org/0000-0002-6749-1436)
- Vittorio Colizzi (ORCID: https://orcid.org/0000-0003-0007-8580)
- Christian Ngongang Ouankou (ORCID: https://orcid.org/0000-0002-1630-4944)
- Michel Carlos Tommo Tchouaket (ORCID: https://orcid.org/0000-0002-7186-8515)
- Aude Christelle Ka’e (ORCID: https://orcid.org/0000-0002-2381-4299)
- Carlo Federico Perno (ORCID: https://orcid.org/0000-0002-0825-5388)
- Rachel Audrey Nayang Mundo (ORCID: https://orcid.org/0000-0002-0479-3840)
- Davy-Hyacinthe Gouissi Anguechia
- Désiré Takou
- Willy Leroi Togna Pabo
- Samuel Martin Sosso
Institutions
- University of Rome Tor Vergata (IT)
- Université de Yaoundé I (CM)
- University of Buea (CM)
- Université de Dschang (CM)
- University of Milan (IT)
- Centre International De Reference Chantal Biya (CM)
- Africa Centres for Disease Control and Prevention (ET)
- Bambino Gesù Children's Hospital (IT)
- WWF Cameroon (CM)
- National Radiation Protection Agency of Cameroon (CM)
- Ministry of Public Health (CM)
- Catholic University of Central Africa (CM)
Publication Details
- Journal
- BMC Infectious Diseases
- Published
- 2025-05-05
- DOI
- https://doi.org/10.1186/s12879-025-11048-5
- Primary Topic
- COVID-19 epidemiological studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- European and Developing Countries Clinical Trials Partnership