The application value of systematic nursing in severe acute pancreatitis patients undergoing blood purification treatment

This study aimed to assess the effects of systematic nursing on severe acute pancreatitis (SAP) patients undergoing continuous renal replacement therapy (CRRT). In this retrospective cohort study, data from SAP patients who received CRRT in our hospital's ICU from January 2022 to January 2024 were analyzed. Patients were grouped based on nursing care type: the experimental group (systematic nursing, 41 cases) and the control group (routine nursing, 59 cases). Observed indicators included vital sign stability, pain and anxiety scores, serum biochemical markers (serum amylase, C-reactive protein [CRP], and white blood cell count), complication rates, and nursing satisfaction. Propensity score matching was used to control for baseline differences. The experimental group demonstrated superior clinical outcomes compared to the control group, with significantly more stable body temperature (36.76 ± 0.31°C vs 37.05 ± 0.45°C, P = .036) and heart rate (82.1 ± 5.7 bpm vs 84.9 ± 6.6 bpm, P = .046). Pain (3.2 ± 1.1 vs 4.5 ± 1.3, P = .012) and anxiety scores (2.8 ± 0.9 vs 3.6 ± 1.0, P = .021) were also significantly lower. Inflammatory markers such as serum amylase (95.4 ± 30.2 vs 120.5 ± 35.8, P = .004), CRP (7.2 ± 3.1 vs 10.3 ± 3.5, P = .005), and white blood cell count (8.5 ± 2.0 vs 10.1 ± 2.6, P = .007) decreased significantly in the experimental group. Furthermore, the experimental group had lower complication rates than the control group (MODS incidence: 23.53% vs 73.53%, P = .030; infection rate: 29.41% vs 88.24%, P = .014; renal insufficiency incidence: 14.71% vs 58.82%, P = .026) and higher nursing satisfaction (P = .041). Systematic nursing significantly improved clinical outcomes in SAP patients receiving CRRT, enhancing vital sign stability, reducing pain and anxiety, controlling inflammation, decreasing complication rates, and increasing nursing satisfaction. These results support the use of systematic, individualized nursing in managing critically ill SAP patients.