Molecular mechanisms explaining sex-specific functional connectivity changes in chronic insomnia disorder
This study uncovered both shared and sex-specific connectivity alterations in CID, providing molecular insights into its pathophysiology and suggesting considering sex differences in future fMRI-based diagnostic and treatment strategies.
Authors
- Liyong Yu (ORCID: https://orcid.org/0000-0002-2916-1903)
- Wenting Lin (ORCID: https://orcid.org/0000-0002-1374-3087)
- Siyi Yu (ORCID: https://orcid.org/0000-0001-7220-3278)
- Zhifu Shen (ORCID: https://orcid.org/0000-0001-6781-4058)
- Wei Wei (ORCID: https://orcid.org/0000-0002-8751-9205)
- Zeyang Dou
- Daijie Hu
- Xiaojuan Hong (ORCID: https://orcid.org/0000-0002-7364-0127)
- Guangli Zhao
- Yucai Luo
Institutions
- North Sichuan Medical University (CN)
- Affiliated Hospital of North Sichuan Medical College (CN)
- Chengdu University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- BMC Medicine
- Published
- 2025-05-05
- DOI
- https://doi.org/10.1186/s12916-025-04089-9
- Citations
- 4
- Primary Topic
- Tryptophan and brain disorders
- Type
- article
- Field-Weighted Citation Impact
- 2.31
Funders
- National Natural Science Foundation of China
- Chengdu University of Traditional Chinese Medicine
- Chengdu University