Serum Lenvatinib and Interleukin-6 Profiles and Their Relationship With Acute Heart Failure Development in a Patient With Thymic Carcinoma and Cancer Inflammation

These findings suggest that elevated serum IL-6 levels lead to delayed elimination of lenvatinib. The increased serum levels of both lenvatinib and IL-6 may be associated with the development of acute heart failure in patients with thymic carcinoma.

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Publication Details

Journal
Therapeutic Drug Monitoring
Published
2025-05-02
DOI
https://doi.org/10.1097/ftd.0000000000001335
Primary Topic
Myasthenia Gravis and Thymoma
Type
article
Field-Weighted Citation Impact
0.00
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article

Serum Lenvatinib and Interleukin-6 Profiles and Their Relationship With Acute Heart Failure Development in a Patient With Thymic Carcinoma and Cancer Inflammation

Tomonobu Koizumi, Yasuaki Mino, Takafumi Naito, Mitsutoshi Asakura et al.
Therapeutic Drug Monitoring
Myasthenia Gravis and Thymoma
article

Serum Lenvatinib and Interleukin-6 Profiles and Their Relationship With Acute Heart Failure Development in a Patient With Thymic Carcinoma and Cancer Inflammation

Tomonobu Koizumi, Yasuaki Mino, Takafumi Naito, Mitsutoshi Asakura, Takashi Kobayashi, Natsumi Seki
article en

Abstract

These findings suggest that elevated serum IL-6 levels lead to delayed elimination of lenvatinib. The increased serum levels of both lenvatinib and IL-6 may be associated with the development of acute heart failure in patients with thymic carcinoma.

Therapeutic Drug MonitoringVol. 47(5)
Shinshu University (JP), Hamamatsu University School of Medicine (JP), Shinshu University Hospital (JP)
Good health and well-being
Openalex Percentile: Top 84%
Myasthenia Gravis and Thymoma
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Serum Lenvatinib and Interleukin-6 Profiles and Their Relationship With Acute Heart Failure Development in a Patient With Thymic Carcinoma and Cancer Inflammation — Tomonobu Koizumi, Yasuaki Mino, et al. · Therapeutic Drug Monitoring (2025) | TGRS Research Map | TGRS