Altered brain activation during memory retrieval mediates the relationship between developmental trauma and psychotic symptom severity
These findings suggest a role of episodic memory processing and inferior parietal lobe activation in the association between DT and psychosis. Focusing further on these measures could provide insight into the underlying mechanism of this association, and have clinical implications in trauma-exposed individuals with psychosis.
Authors
- Barbara A. Cornblatt (ORCID: https://orcid.org/0000-0002-3194-6304)
- Diana O. Perkins (ORCID: https://orcid.org/0000-0001-9396-2206)
- Carrie E. Bearden (ORCID: https://orcid.org/0000-0002-8516-923X)
- Daniel H. Mathalon (ORCID: https://orcid.org/0000-0001-6090-4974)
- Elaine F. Walker (ORCID: https://orcid.org/0000-0002-9798-8101)
- Hengyi Cao (ORCID: https://orcid.org/0000-0003-4168-0391)
- Scott W. Woods (ORCID: https://orcid.org/0000-0002-3103-5228)
- Donald Addington (ORCID: https://orcid.org/0000-0002-0527-0275)
- Kristin S. Cadenhead (ORCID: https://orcid.org/0000-0002-5952-4605)
- Tyrone D. Cannon (ORCID: https://orcid.org/0000-0002-5632-3154)
- Ava Mason (ORCID: https://orcid.org/0000-0001-7932-3459)
- William Palmer
Institutions
- University of North Carolina at Chapel Hill (US)
- Feinstein Institute for Medical Research (US)
- Emory University (US)
- University of Calgary (CA)
- University of California, San Francisco (US)
- Yale University (US)
- University of California San Diego (US)
- Neurobehavioral Systems (US)
- The London College (GB)
- Zucker Hillside Hospital (US)
- University College London (GB)
Publication Details
- Journal
- Schizophrenia Research
- Published
- 2025-05-05
- DOI
- https://doi.org/10.1016/j.schres.2025.04.034
- Primary Topic
- Child and Adolescent Psychosocial and Emotional Development
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Alkermes
- National Institute of Mental Health and Neurosciences
- National Institutes of Health
- National Institute of Mental Health