Sugarcane Molasses Polyphenol Extract Attenuates Alcohol-Induced Chronic Liver Damage via Antioxidant, Anti-Inflammatory, and CYP2E1/Keap1/NF-κB Pathway Modulation
The findings reveal that SP mitigates ALD via synergistic antioxidant and anti-inflammatory mechanisms, providing a novel strategy for high-value utilization of sugarcane molasses byproducts in agricultural industries. Future studies should focus on the contribution of the different phenolics in SP and validate their specific hepatoprotective mechanisms.
Authors
- Chengfeng Zhang (ORCID: https://orcid.org/0000-0002-1302-5667)
- He Li (ORCID: https://orcid.org/0000-0001-7459-9202)
- Min Wang (ORCID: https://orcid.org/0000-0002-8365-8435)
- Lin Zhao (ORCID: https://orcid.org/0000-0003-2567-627X)
- Yumei Wang (ORCID: https://orcid.org/0000-0003-0685-6881)
Institutions
- Beijing Technology and Business University (CN)
Publication Details
- Journal
- Nutrients
- Published
- 2025-05-05
- DOI
- https://doi.org/10.3390/nu17091589
- Citations
- 3
- Primary Topic
- Alcohol Consumption and Health Effects
- Type
- article
- Field-Weighted Citation Impact
- 4.41
Funders
- National Key Research and Development Program of China