Hypertension modifies the association between serum Klotho and chronic kidney disease in US adults with diabetes: a cross-sectional study of the NHANES 2007–2016
Among DM adults, hypertension modified the association between sKlotho levels and CKD prevalence. Both additive and multiplicative interactions were observed between hypertension and sKlotho levels on CKD. The causalities between hypertension, Klotho, and CKD in diabetic patients need further exploration, and underlying mechanisms warrants elucidation.
Authors
- Chaojun Zhang (ORCID: https://orcid.org/0000-0003-4543-6978)
- Zhen-Nan Ye (ORCID: https://orcid.org/0000-0002-1237-1971)
- Weihuang Zhang
- Tao Hong (ORCID: https://orcid.org/0009-0007-8355-2984)
- Zhiyun Lian
Institutions
- Guangdong Medical College (CN)
- Affiliated Hospital of Guangdong Medical College Hospital (CN)
Publication Details
- Journal
- Renal Failure
- Published
- 2025-05-05
- DOI
- https://doi.org/10.1080/0886022x.2025.2498089
- Citations
- 3
- Primary Topic
- Parathyroid Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 4.29