EFI Abstracts
mice exhibited increased levels of cytotoxic granules, further supporting the role of ERAP1 in modulating NK cell activity.Overall, our findings indicate that disrupting the inhibitory KIR-HLA-A/B/C and NKG2A-HLA-E axes through ERAP1 inhibition is an attractive therapeutic approach for haematological malignancies.
Publication Details
- Journal
- HLA
- Published
- 2025-05-01
- DOI
- https://doi.org/10.1111/tan.70158
- Primary Topic
- Immune Cell Function and Interaction
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Université de Lille
- Université de Toulouse
- Assistance publique-Hôpitaux de Paris