Enfortumab Vedotin–Induced Toxic Epidermal Necrolysis in Metastatic Urothelial Carcinoma Complicated by Severe Gastrointestinal Bleeding

This case highlights that Stevens-Johnson syndrome/TEN induced by EV can develop shortly after treatment, with delayed and potentially fatal GI manifestations. Given the challenges in managing established TEN, close monitoring for adverse events is essential.

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Publication Details

Journal
IJU Case Reports
Published
2025-05-05
DOI
https://doi.org/10.1002/iju5.70036
Primary Topic
Drug-Induced Adverse Reactions
Type
article
Field-Weighted Citation Impact
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article

Enfortumab Vedotin–Induced Toxic Epidermal Necrolysis in Metastatic Urothelial Carcinoma Complicated by Severe Gastrointestinal Bleeding

Michihiko Kobayashi, Hiroki Hirabayashi, Aika Matsuyama, Asaomi Yamaguchi et al.
IJU Case Reports
Drug-Induced Adverse Reactions
article

Enfortumab Vedotin–Induced Toxic Epidermal Necrolysis in Metastatic Urothelial Carcinoma Complicated by Severe Gastrointestinal Bleeding

Michihiko Kobayashi, Hiroki Hirabayashi, Aika Matsuyama, Asaomi Yamaguchi, Yasuhiko Tsunoda, Masashi Kato, Ayako Momota, Takashi Kato, Shoji Suzuki, R. Kawase
article en

Abstract

This case highlights that Stevens-Johnson syndrome/TEN induced by EV can develop shortly after treatment, with delayed and potentially fatal GI manifestations. Given the challenges in managing established TEN, close monitoring for adverse events is essential.

IJU Case ReportsVol. 8(4)
Japanese Red Cross Nagoya Daiichi Hospital (JP)
Good health and well-being
Openalex Percentile: Top 89%
Drug-Induced Adverse Reactions
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