Sleeping for two: a cross-sectional study on associations between objectively measured sleep during early to mid-pregnancy and maternal and fetal outcomes and inflammatory biomarker profiles
Poor sleep in early to mid-pregnancy was more common in pregnant women with pre-pregnancy diabetes, obesity, and those born outside of Europe. Poor sleep was associated with a higher likelihood of emergency caesarean section, but no other maternal or fetal outcomes. An overall trend was observed towards lower levels of inflammatory markers in women that slept poorly; however, additional studies are needed to better understand the immune system's role in the relationship between sleep, maternal health, and maternal and fetal outcomes. Possible mechanisms underlying these associations warrant further research.
Authors
- Inger Sundström Poromaa (ORCID: https://orcid.org/0000-0002-2491-2042)
- Peter Meerlo (ORCID: https://orcid.org/0000-0002-8330-6050)
- Alkistis Skalkidou (ORCID: https://orcid.org/0000-0002-4935-7532)
- Courtney Macdonald (ORCID: https://orcid.org/0000-0003-2603-4068)
- Tryfonas Pitsillos (ORCID: https://orcid.org/0000-0002-1887-2144)
- Theodora Kunovac Kallak (ORCID: https://orcid.org/0000-0002-2112-8674)
- Jelmer R. Prins (ORCID: https://orcid.org/0000-0002-3984-2163)
- Berend Olivier (ORCID: https://orcid.org/0000-0003-4654-9763)
- Anna-Karin Wikström
Institutions
- Uppsala University (SE)
- University Medical Center Groningen (NL)
- University of Groningen (NL)
Publication Details
- Journal
- BMC Pregnancy and Childbirth
- Published
- 2025-05-05
- DOI
- https://doi.org/10.1186/s12884-025-07634-9
- Citations
- 1
- Primary Topic
- Sleep and related disorders
- Type
- article
- Field-Weighted Citation Impact
- 2.12
Funders
- Akademiska Sjukhuset
- Uppsala Universitet