In vitro Antifungal Susceptibility Profile of Clinical Cladophialophora boppii in Malaysia

In conclusion, all the <i>C. boppii</i> isolates in this study were susceptible to pyrimidine, allylamine, and azoles, while showing intermediate susceptibility to fluconazole and notable resistance to amphotericin B. Additionally, itraconazole and terbinafine could be recommended as the first-line therapy option, which was supported by their demonstrated efficacy (MIC ≤0.03 μg/mL) and clinical improvement observed in this study.

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Publication Details

Journal
Infection and Drug Resistance
Published
2025-05-01
DOI
https://doi.org/10.2147/idr.s513536
Primary Topic
Plant Pathogens and Fungal Diseases
Type
article
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article

In vitro Antifungal Susceptibility Profile of Clinical Cladophialophora boppii in Malaysia

Murnihayati Hassan, Xue Ting Tan, Min Tang, Nurin Nazirah Mokhtar
Infection and Drug Resistance
Plant Pathogens and Fungal Diseases
article

In vitro Antifungal Susceptibility Profile of Clinical Cladophialophora boppii in Malaysia

Murnihayati Hassan, Xue Ting Tan, Min Tang, Nurin Nazirah Mokhtar
article en

Abstract

In conclusion, all the <i>C. boppii</i> isolates in this study were susceptible to pyrimidine, allylamine, and azoles, while showing intermediate susceptibility to fluconazole and notable resistance to amphotericin B. Additionally, itraconazole and terbinafine could be recommended as the first-line therapy option, which was supported by their demonstrated efficacy (MIC ≤0.03 μg/mL) and clinical improvement observed in this study.

Infection and Drug ResistanceVol. Volume 18
Ministry of Health (MY), Sarawak General Hospital (MY), Institute for Medical Research (MY)
Zero hunger
Openalex Percentile: Top 90%
Plant Pathogens and Fungal Diseases
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