Therapeutic gene targets and epigenetic modifications in rheumatoid arthritis: Insights from MTX, JAK inhibitors, and LLDT-8
This study highlights therapeutic gene targets and their epigenetic modifications as potential mechanisms underlying the effects of MTX, JAK inhibitors, and LLDT-8 in RA treatment. <i>GALNT9</i> and <i>CCNF</i> emerge as promising candidates for further exploration in targeted therapeutic strategies.
Authors
- Chenyang Song
- Yu Shan (ORCID: https://orcid.org/0000-0003-0979-695X)
- Yixin Zheng
- Jun‐Yu Fan (ORCID: https://orcid.org/0000-0003-4002-523X)
- Yuejuan Zheng (ORCID: https://orcid.org/0000-0001-9995-4960)
- Yiming Shi (ORCID: https://orcid.org/0009-0009-9584-0830)
- Cen Chang (ORCID: https://orcid.org/0000-0002-7449-2613)
- Dongyi He (ORCID: https://orcid.org/0000-0001-7975-3870)
- Runrun Zhang (ORCID: https://orcid.org/0000-0002-9948-6332)
- Yaxin Cheng
- Jianan Zhao
- Fuyu Zhao
- Yunshen Li
Institutions
- Zhejiang Chinese Medical University (CN)
- Shanghai University of Traditional Chinese Medicine (CN)
- Shanghai Guanghua Hospital of Integrated Traditional Chinese and Western Medicine (CN)
Publication Details
- Journal
- Biochemistry and Biophysics Reports
- Published
- 2025-05-05
- DOI
- https://doi.org/10.1016/j.bbrep.2025.102038
- Citations
- 1
- Primary Topic
- Cytokine Signaling Pathways and Interactions
- Type
- article
- Field-Weighted Citation Impact
- 1.05